北京和南京两地代谢综合征危险因素分析

Multivariate analysis on the risk factors of metabolic syndrome in Beijing and Nanjing

目的分析北京和南京两地人群代谢综合征的危险因素。方法采用整群抽样对北京和南京的6 123人进行流行病学调查,应用IDF(2005)定义。采用多因素Logistic回归分析可能存在的危险因素。结果男性和女性的年龄标化患病率分别为19.5%和33.6%。多因素条件Logis-tic回归结果,女性(OR=1.49;95%CI(1.40,1.59))、年龄增长(OR=1.23;95%CI(1.16,1.31))、低体力活动(OR=1.76;95%CI(1.13,2.76))、糖尿病家族史(OR=1.33;95%CI(1.11,1.60))、高血压家族史(OR=1.46;95%CI(1.29,1.65))、年龄性别交互作用(OR=1.29;95%CI(1.21,1.40))、居住在城市(OR=1.09;95%CI(1.02,1.18))均是代谢综合征的危险因素。居住在南京(OR=0.76;95%CI(0.71,0.81))是代谢综合征的保护因素。结论代谢综合征是多重危险因素共同作用的结果,其中女性、慢病家族史、低体力活动是其重要的危险因素。

Objective To explore the risk factors of metabolic syndrome in Beijing and Nanjing. Methods Using identical protocol and questionnaire,an epidemiological study was carried out in a population of 6 123 adults in Beijing and Nanjing. IDF （2005） was used as the diagnostic criteria of metabolic syndrome. Univariate and multivariate Logistic regression model were used to identify risk factors. Results The age-standardized prevalence of metabolic syndrome in males and females were 19.5 % and 33.6 %, respectively. The results of multivariate logistic regression analyses showed that female （ OR = 1.49 ; 95 % CI （1.40,1.59） ）, age increasing （ OR = 1.23 ; 95 % CI （ 1.16,1.31 ） ）, low physical activity （OR=1.76;95% CI（1. 13,2.76））, with diabetes family history （OR = 1.33;95% CI（1.11, 1.60） ）, with hypertension family history （ OR = 1.46 ; 95 % CI （ 1.29,1.65 ） ）, the interaction of age and gender （0R=1.29;95% CI（1.21,1.40））, live in Urban （OR=1.09;95% CI（1.02,1.18）） could significantly increase the risk of disease development. On the other hand, live in Nanjing （OR = 0.76 ;95 % CI （0.71,0.81） ） can perform the protective effect. Conclusions Metabolic syndrome was the common results of a variety of risk factors. Female, with chronic disease family history and low physical activity are important risk factors.