儿童食用含三聚氰胺奶粉致泌尿系统结石的相关因素分析

Related factors of children's consumption of milk containing melamine induced urinary system calculus

目的探讨在三聚氰胺奶粉事件中,儿童患泌尿系统结石与食用含三聚氰胺奶粉的相关危险因素及危险程度。方法采用整群筛查方法,对8岁以下食用奶粉的儿童进行泌尿系统超声检查和问卷调查,随机抽取159例泌尿系统结石患儿和222例无泌尿系统结石儿童,将资料整理并进行两独立样本t检验、χ2检验和多因素Logistic回归分析。结果食用含三聚氰胺奶粉的儿童患泌尿系统结石的奶粉相关危险因素有奶粉品种(OR=2.680,95%CI:1.643～4.371),食用时间(OR=1.398,95%CI:1.039～1.882),食用时间比(OR=1.676,95%CI:1.344～2.091)。结论食用含三聚氰胺奶粉的儿童患泌尿系统结石的奶粉相关危险因素主要为奶粉品种、食用时间、食用时间比,患泌尿系统结石的危险性与食用时间、食用时间比呈正相关,食用高浓度三聚氰胺奶粉的危险性明显高于低浓度三聚氰胺奶粉。

Objective To explore and analyze the related factors of melamine milk powder and children urinary system stones. Methods Use of cluster screening methods, children under the age 8 were examined by ultrasound. Random sample of 159 children with urinary stones, and 222 normal children were recruited, their survey data were analyzed by means of independent samples t test, Chi-square test and multi-factor logistic regressions. Results Analysis shows that melamine milk powder-related risk factors for children urinary system calculus of varieties of milk powder （ OR = 2. 680, 95 % CI ： 1. 643 4. 371 ）, milk consumption time （ OR = 1. 398,95 % CI ： 1. 039 -- 1. 882）, milk consumption time ratio （ OR = 1. 676, 95 % CI ： 1. 344-- 2. 091）. Conclusions Melamine milk for children, the risk of suffering from urinary system calculus include varieties of milk, milk consumption time, milk consumption time ratio. Milk consumption time ratio and varieties of milk are important influencing factors. Both milk consumption time ratio and milk consumption time are related to children urinary system calculus. High level melamine milk powder has higher risk than low level.