河南省预防艾滋病母婴传播工作效果评价

Evaluation of AIDS Prevention in Transmission Mother to Child in Henan Province

目的了解河南省开展预防艾滋病母婴传播阻断工作的效果,探讨母婴传播的影响因素。方法收集自2001年1月至2008年6月底通过HIV检测和HIV阳性育龄妇女随访工作中发现的HIV阳性产妇及其分娩婴儿的有关信息,比较产妇和婴儿的干预措施对预防艾滋病母婴传播效果的影响。结果352名HIV阳性产妇分娩的362名婴儿中,满18月龄HIV抗体检测有344名阴性,18名阳性,实施药物阻断组母婴传播率3.5%(12/339),未实施药物阻断组母婴传播率26.1%(6/23),组间有统计学意义(χ2=19.95,P<0.01);婴儿采取不同的喂养方式,HIV母婴传播率不同,组间有显著性差异(χ2=14.74,P<0.01);药物干预情况下,分娩方式不同母婴传播率组间无显著性差异。结论为感染艾滋病病毒(HIV)的产妇提供安全的住院分娩服务及合理规范的药物阻断,采取人工喂养,有效降低了母婴传播的危险,预防艾滋病母婴传播工作降低了艾滋病的二代传播率。

Objective To assess the effectiveness of relevant interventions and study the risk factors of HIV mother to children transmission in Henan province. Methods Collect the data of HIV positive pregnant and their newborns since January 2001 to the end of June 2008, a comparison of maternal and infant intervention measures were conducted to study the impact on the rate of MTCT. Results The were 18 infants infected with HIV and 344 infants were tested as HIV negative among the tested 362 infants. The rate of MTCT is 3.5% among the group with the intervention adopted and it was 26.1% among the group which have no intervention measures. There were significant difference between these two groups（Χ^2 = 19.95, P 〈0.01 ） ; The rate of mother to child transmission of different feeding patterns were significantly different （Χ^2 =14.74, P 〈0.01 ） ; the birth mother to child transmission rate in different ways intergroup difference was not significantly. Conclusion To provide a safe maternity hospital maternity services and a reasonable drug to block riorms to be effective in reducing the risk of mother to child transmission, Adopts artificial feeding, reduced the maternal infant transmission danger effectively, prevented AIDS maternal infant transmission work to reduce the AIDS two generation of dissemination rate.