Hofmann重排法合成苯氨基甲酸酯

Synthesis of Phenyl Carbamate by Hofmann Rearrangement

采用一种新型的溴化试剂１，３二溴５，５二甲基海因（ＤＢＤＭＨ），在醋酸汞（Ｈｇ（ＯＡｃ）２）存在下，使苯甲酰胺发生Ｈｏｆｍａｎｎ重排，经异氰酸酯中间体，与醇作用，合成了苯氨基甲酸酯．

Phenyl carbamate has been synthesized from benzamide by using a new brominating agent—DBDMH and making Hofmann rearrangement occured in it in the presence of Hg(OAc) 2 via intermediates, isocyanate reacting with alcohol.