早期脑血管病的微循环表现

Analysis of Relationship between Disturbance of Microcirculation and Early Stage of Cerebrovascular Diseases

通过对血液微循环观测，分析微循环障碍与早期脑血管病发生率的相关性。方法：采用微循环显微镜观察人体甲襞微循环的微血管和微血流的动态变化。结果：微循环障碍患者，表现明显微血管痉挛性和淤滞性改变，由于微循环灌注减少，加重组织缺血缺氧，微血栓形成。结论：微血管及微血流的异常影响人体机能代谢的变化，导致微血管内皮损伤、血液的凝固性增强，而外周血流及血管的异常改变，同样可影响脑血流量及供血。提示微循环障碍与早期脑血管病密切相关。对早期预防、诊断具有重要参考价值。

Objective: The relationship between disturbance of microcirculation and incidence of early stage of cerebrovascular diseases were observed by microcirculatory microscope. Methods: Microcirculatory microscope was used to observe the dynamic changes of microvessels and microcirculatory blood flow of nailfold of the human body. Results: In patients of spasticity of microvessels and pooling occurred, because of decrease of microcirculation perfusion, ischemia and hypoxia of the tissues were exacerbrated and microthrombosis appeared. Conclusion: Abnormality of microvessels and microcirculation flow influences the changes of the functions and the metabolism of the body, leads to injure of the endothelia of the microvessels, increases the ability of the blood coagulation.The abnormal changes of the peripheral blood flow and the vessels, may also influence the cerebral blood volume and blood supply. Therefore, it is suggest that the disturbance of microcirculation is closely correlated with the early stage of cerebrovascular diseases. The results are very meaningful for early prevan tion and diagnosis.