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单发与多发乳腺纤维腺瘤中雌激素受体的表达差异及意义 被引量:2

Expression Differences of ER between Single and Multiple Fibroadenoma and Their Significance
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摘要 目的:检测雌激素受体(ER)在单发与多发(肿瘤个数≥2个)乳腺纤维腺瘤中的表达,观察单发与多发乳腺纤维腺瘤复发率的差异。方法:80例单发与80例多发乳腺纤维腺瘤光镜下回顾性观察,并对肿瘤组织进行ER免疫组织化学染色。结果:ER在单发纤维腺瘤与多发纤维腺瘤中的表达阳性率分别为61.2%和77.5%,P<0.05。术后3年,80例多发乳腺纤维腺瘤有19例复发,而80例单发者3例复发,P<0.05。结论:多发纤维腺瘤的ER表达阳性率大于单发者,多发纤维腺瘤的复发率大于单发者。 Objective:To detect the expressions of estrogen reeeptor(ER) in single and multiple breast fibroadenoma tissue and observe the differences of the recrudescence rate between single and multiple fibroadenoma tissue.Methods: Observation of eighty eases of single breast fibroadenoma and eighty cases of multiple breast fibroadenoma retrospectively under the light microscope, and performance of staining for ER in tumor tissues. Result: Positive expression rates for ER in single and multiple fibroadenoma tissue are 61% and 78%,P 〈0.05.3 years after operation, there are 19 cases recrudescent in eighty cases of multiple fibroadenoma.and 3 cases reerudescent in eighty cases of single fibroadenoma, P 〈0.05.Conclusion:The ER-positive rate of multiple fibroadenoma is higher than single persons. The recrudescence rate of multiple fibroadenoma is higher than single persons.
出处 《实用中西医结合临床》 2009年第6期66-67,共2页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
关键词 乳腺纤维腺瘤 雌激素受体 阳性率 复发 Breast fibroadenoma Estrogen receptor Positive expression rate Recrudescent
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参考文献7

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