He-Ne激光照射对骨折愈合过程中血清羟脯氨酸的影响

EFFECTS OF He Ne LASER IRRADIATION ON CONCENTRATION OF SERUM HYDROXYPROLINE IN PROCESS OF RABBIT FRACTURE HEALING

研究了三个不同剂量的Ｈｅ－Ｎｅ激光照射对骨折愈合过程中血清羟脯氨酸浓度的影响。将３２只新西兰白兔的左桡骨造成实验性骨折，将之分为四组，分别接受：Ａ）３６Ｊ／ｃｍ２、Ｂ）１６．８Ｊ／ｃｍ２、Ｃ）４．８Ｊ／ｃｍ２、Ｄ）０Ｊ／ｃｍ２（对照）的Ｈｅ－Ｎｅ激光照射，每日１次，共照１０次，直接照射骨折部位。测定不同时期血清中羟脯氨酸浓度。结果：在骨折愈合初期，Ｂ和Ｃ组血清羟脯氨酸浓度均显著优于对照组，且Ｂ组显著优于Ｃ组；Ａ组与对照组比较，对照组显著优于Ａ组。表明：１６．８Ｊ／ｃｍ２和４．８Ｊ／ｃｍ２的Ｈｅ－Ｎｅ激光照射刺激了骨折愈合，且１６．８Ｊ／ｃｍ２效果更佳；

The effects of three levels of energy density He Ne laser on the concentration of serum hydroxyproline in the Process of rabbit fracture healing were studied.Thirty two rabbits randomized into A,B,C and control groups received respectively 36J/cm 2,16.8J/cm 2,4.8J/cm 2,0J/cm 2 He Ne laser irradiation.Their concentration of serum hydroxyproline were examined on the 5th,10th,15th,20th,25th amd 30th day postfracturally.The result showed that during 15 days after the fracture,the concentration of serum hydrocyproline in Group B and Group C were significantly higher than that in the control group,the concentration in Group B was significantly higher than that in Group C, and the concentration in the control group was significantly higher than that in Group A.It is suggested that 16.8J/cm 2 and 4.8J/cm 2 He Ne laser irradiation could stimulate the fracture healing,16.8J/cm 2 could be the best level of the three energy densities,but 36J/cm 2 He Ne laser could inhibit the fracture healing.