复合磷酸酯酶片联合苦参素胶囊治疗慢性乙型肝炎疗效观察

Clinical observervation on the results in treatment of chronic hepatitis B with phosphoesteraum compositurn combined with marine capsules

目的探讨复合磷酸酯酶片联合苦参素胶囊治疗慢性乙型病毒性肝炎的临床治疗作用。方法将89例乙肝患者随机分为2组，实验组应用复合磷酸酯酶片及苦参素胶囊，对照组单纯服用苦参素胶囊，检测治疗后2组谷丙转氨酶（AIJT）、谷草转氨酶（AST）、谷胺酰转肽酶（γ-GT）、总胆红素（TBil）及HBV—DNA。结果90d后联合药物组ALT、AST、γ一GT、TBil及HBV．DNA改善明显，与对照组相比，具有统计学差异，P〈0．05，且联合用药组及对照组均未发现明显不良反应。结论复合磷酸酯酶片联合苦参素胶囊在临床上治疗慢性乙型肝炎具有良好疗效。

Objective To observe the therapeutic effectiveness of phosphoesterasum compositum combined with marine capsules for chronic hepatitis B. Methods There 89 patients with Chronic hepatitis B were divided into treatment and control groups. The patients in control group only received Marine Capsules. Those in the treatment group were treated with phosphoesterasum compositum and marine capsules. 90 days after treatment the levels of alanine transaminase （ ALT）, aspartate aminotransferase （ AST）, γ-glutamyl transpeptidase （ γ-GT）, total bilirubin （ TBil）, HBV-DNA were determined. Results In treatment group, the levels of ALT, AST, γ-GT, TBil, HBV-DNA were obviously improved as compared with those of the control group. Conclusion Phosphoesterasum compositum combined with marine capsules is effective for treatment of patients with Chronic hepatitis B.