盐酸地芬尼多片含量测定方法研究

A METHOD FOR DETELTION THE CONTENTS OF DIFENIDOL HYDROCHLORIDE TABLETS

本文报道盐酸地芬尼多片的高效液相色谱测定方法。在ODS柱上以甲醇－辛烷磺酸钠（0．05mol／L）离子对液50：50为流动相，盐酸地芬尼多与制剂辅料完全分离，可用于溶出度的测定。方法准确、快速、灵敏度高。

HPLC Method For the determination of difenidol Hydrochloride Tablets was reported. On the ODS-Column. We used methylic alcohol: l-octanesulfonic acid sodium (0. 05mol/L);the ion pare liquid 50: 50 as the mobile phase. The Difenidol Hydrochloride Tablets was separated from related compounds' Dissolutionrate of the Defenidol Hydrochloride Tablets was successfully analysed by this method. The method was very rapid accurate and has high sensitivity.