摘要
目的：改进大鼠原位肝移植的手术操作方法。方法：采用远交系Ｗｉｓｔａｒ和远交系ＳＤ大鼠，用二袖套法（门静脉和肝下下腔静脉）建立大鼠原位肝移植模型，正式实验４６次。结果：改进了供肝获取和安装血管套管方法，受体无肝期平均１９ｍｉｎ，手术成功率达９１．３％。结论：改进的大鼠原位肝移植术操作简便，手术成功率较高，可做为肝移植实验可靠。
Abstract Objective:To modify an experimental rat orthotopic liver transplantation model.Methods:Two cuff(portal vein and infrahepatic vena cava) technique was applied in the production of this animal model in Wistar rats and SD rats.Results:With the modifiation,a successful rate of 91 3% was archieved in the production of the experimental model with anhepatic period of on average 19 minutes.Conclusion:The modified model is easily available and highly reproducible,which provides a practical and stable experimental model for the study of liver transplantation. Subject Headings:rats;surgery operative;liver transplantation
出处
《中日友好医院学报》
1998年第4期287-290,共4页
Journal of China-Japan Friendship Hospital
基金
国家教委资助
