摘要
目的:观察老年人牙周炎龈组织T和B淋巴细胞免疫组织化学变化。方法:对15例老年牙周炎患者龈组织进行常规组织病理学检查,同时采用ABC法对IgA、IgG、IgM、λ、κ、CD4和CD8阳性细胞进行免疫组织化学染色观察,计算CD4:CD8的比值。结果:IgM阳性细胞阳性率明显高于IgA阳性细胞阳性率(P<0.05),CD4:CD8的比值降低。结论:老年人牙周炎龈组织免疫功能可能降低。
Aim: To observe immunohistochemical characteristics of T and B lymphocytes in old periodontitis patients. Methods: Gingiva tissues from 15 cases of old periodontitis patients had been stained histologically and had been labelled immunohistochemically with monoclonal antibodies for IgA, IgG, IgM, κ,λ,T4(CD4), T8(CD8). Then we calculated T4:T8 lymphocyte ratio. Results: In old periodontitis patients, the positive cases of IgM were more than those of IgA significantly.(P<0.05). T4:T8 lymphocyte ratio decreased significantly. Conclusions: Immunological function in gingiva tissue of old periodontitis patients may be low. Its histological and immunohistochemical characteristics are different from periodontitis patients of other aged groups.
出处
《牙体牙髓牙周病学杂志》
CAS
1998年第4期240-242,共3页
Chinese Journal of Conservative Dentistry
关键词
老年人
牙周炎
免疫组织化学
T淋巴细胞
old periodontitis patient T and B Lymphocyte immunohistochemical study