山东省糖尿病患病现况与流行因素研究

Study on the Prevalence and Risk Factors of Diabetes Mellitus in Shandong Province

以分层整群随机抽样方法对２０２２８人糖尿病患病情况进行了流行病学调查，结果发现：总患病率为１０．９３‰，ＩＤＤＭ占４．５％，ＮＩＤＤＭ占９５．５％；总患病率随年龄递增，≥６０岁达５５．６‰；城市患病率（２３．５‰）最高，其次为海岛、沿海居民（２１．４‰），农村最低（４．２２‰）；男、女患病率差异无显著性；调查中新诊断的病人占病人总数３３．５％。对２１１例ＮＩＤＤＭ患者进行的流行因素的病例对照分析发现：最终进入多因素Ｌｏｇｉｓｔｉｃ回归模型有意义的因素有家族史系数、ＢＭＩ、喜素食和高血压，ＯＲ值分别为３．３２、２．８９、０．３８和１．６７。交互作用分析表明，阳性家族史与体重超重或不良饮食习惯二因素并存者。

A total of 20 228 subjects were selected by the method of stratified random cluster sampling and studied.Results showed that the total prevalence rate was 10.93‰.IDDM accounts for 4.5%,NIDDM accounts for 95.5%.The prevalence was increased with age,up to 55.6‰ of that ≥60 years.The highest prevalence rate was in the population of city( 23.5 ‰) and the lowest was that of rural(4.22‰).Prevalence difference between male and female was not statistically significant.The new cases diagnosed by the study account for 33.5%,and this proportion got up to 51% in the rural area.The results of a case control study on the risk factors of 211 NIDDM cases showed that family diabetes history,BMI,favour of vegetarian diet and hypertension were significantly correlated to NIDDM in the model of multifactorial Logistic regression. OR values were 3.32,2.89,0.38,and 1.67 respectively.According to the interaction analysis,those having family DM history,overweight or unhealthy diet habit coexist,especially those with the three factors coexist should be the key population of the community intervention program of the disease.