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影响胚胎冻融的临床因素和妊娠结局分析 被引量：1

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摘要 目的:探讨新鲜周期中有无剩余胚胎冷冻的相关因素和胚胎冻融移植周期影响妊娠的临床因素,比较冷冻周期和新鲜周期出生婴儿状况。方法:回顾性分析2003年1月～2005年12月在南京鼓楼医院生殖医学中心行IVF/ICSI的妇女,根据取卵后有无冷冻胚胎分为有冷冻胚胎组(A组)和无冷冻胚胎组(B组);新鲜周期失败的妇女根据胚胎解冻移植后妊娠与否分为妊娠组(a组)和未妊娠组(b组)。结果:共1593个新鲜周期和817个冷冻周期纳入研究,结果发现:①A组较B组患者年轻(29.91岁vs31.97岁),平均获卵数多(14.23vs9.03);②胚胎冻融结局主要与患者年龄相关,与血清E2水平、子宫内膜厚度和胚胎受精方式无显著相关性;③冷冻周期与新鲜周期出生婴儿状况相比无显著差异。结论:年轻和获卵数较多的患者,有冷冻胚胎的可能性较大;胚胎冻融结局主要与患者年龄相关,与血清E2水平、子宫内膜厚度和胚胎受精方式无显著相关性;冷冻周期出生婴儿状况与新鲜周期相比无显著差异。
作者 陈骞 孙海翔 胡娅莉 王玢 张宁媛
机构地区 上海交通大学医学院附属瑞金医院生殖医学中心 南京大学医学院附属鼓楼医院生殖医学中心
出处 《中国妇幼保健》 CAS 北大核心 2009年第35期5040-5042,共3页 Maternal and Child Health Care of China
关键词 胚胎冷冻 体外受精 妊娠结局
分类号 R321 [医药卫生—人体解剖和组织胚胎学]
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参考文献9

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共引文献25

同被引文献10

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中国妇幼保健
2009年 第35期

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