摘要
为探讨不同中医证候的支气管哮喘患者血清IgE的变化,选择中医辨证为肺热、肺寒、肺气虚、肾阳虚、肾阴虚的患者各40例,采用双抗体夹心(ELISA)法,对其进行血清总IgE(cIgE总)测定。结果发现:哮喘患者存在不同程度的血清IgE变化,并发现其cIgE总水平的变化与中医证候存在一定关系,其中肺热和肾阴虚证患者血清cIgE总升高明显(P<0.001),而肺寒、肺气虚和肾阳虚证患者血清IgE升高不明显(P>0.05),部分患者有下降趋势。该结果在一定程度上提示了中医不同证候在该病患者中的物质性基础。
To investigate the relationship between serum IgE and TCM syndromes, the total blood IgE (TIgE) in 40 cases of bronchial asthma(BA) with the syndromes of lung_heat, lung_cold, lung_Qi deficiency, kidney_Yang deficiency and kidney_Yin deficiency were determined with ELISA(enzyme linked immunosorbent assay). The results showed that the contents of TIgE in cases with the syndromes of lung_heat and kidney_Yin deficiency markedly increased(P<0.001),while those in the syndromes of lung_cold, lung_Qi deficiency and kidney_Yang deficiency showed no changes (P>0.05), even decreased in some cases. It is indicated that there is a certain relationship between serum IgE and TCM syndromes. [WT5”HZ〗
出处
《广州中医药大学学报》
CAS
1998年第4期254-257,共4页
Journal of Guangzhou University of Traditional Chinese Medicine
关键词
哮喘
病理生理学
病机
免疫球蛋白类
ASTHMA/physiopathol.
ASTHMA/pathegenesis(TCM)
IMMUNOGLOBULINS/blood
LUNG_QI DEFICIENCY/pathogenesis(TCM)
KIDNEY DEFICIENCY/pathogenesis(TCM)