5M aggioni AP,L atini R,Carson PE,et al. Valsartan reduces the incidence of at2 rial fibrillation in patients with heart failure:results from the valsartan Heart Failure TraiI(VaI2HeFT)[J]. Am Heart J, 2005,149 : 5482557.
6Ducharm e A,Swedberg K,Pfeffer MA,et ah Prevention of atrial fibrillation in patients with symp tom atic chronic heart failure by candesartan in the Candesar2 tan in Heart failure:A ssessm ent of Reduction in Mortalityand Morbidity (CHARM) program[J]. Am Heart J,2006,152(1) :86292.
2Li D,Fareh S,Leung TK,et al.Promotion of atrial fibrillation by heart failure in dogs:atrial remodeling of a different sort[J].Circulation,1999,100(1):87-95.
3Brundel BJ,Henning RH,Kampinga HH,et al.Molecular mechanisms of remodeling in human atrial fibrillation[J].Cardiocvasc Res,2002,54(2):315-324.
4Goette A,Staack T,Rcken C,et al.Increased expression of extracellular signal-regulated kinase and angiotensin-converting enzyme in human atria during atrial fibrillation[J].J Am Coll Cardiol,2000,35(5):1669-1677.
5Boldt A,Wetzel U,Weigl J,et al.Expression of angiotensin Ⅱ receptors in human left and right atrial tissue in atrial fibrillation with and without underlying mitral valve disease[J].J Am Coll Cardiol,2003,42(10):1785-1792.
7Willems R,Sipido KR,Holemans P,et al.Different patterns of angiotensinⅡand atrial natriuretic peptide secretion in a sheep model of atrial fibrillation[J].J Cardiovasc Electrophysiol,2001,12:1387-1392.
8Ausma J,Dispersyn G,Hans D,et al.Changes in ultra structural calcium distribution in goat atria during atrial fibrillation[J].J Mol Cell Cardiol,2000,32 (6):355-364.
9Brundel BJ,van Gelder IC,Henning RH,et al.Ion channel remodeling is related to intraoperative atrial effective refractory periods in patients with paroxysmal and persistent atrial fibrillation[J].Circulation,200l,103(5):684-690.
10Gassanov N,Brandt MC,Michels G,et al.Angiotensin Ⅱ-induced changes of calcium sparks and ionic currents in human atrial myocytes:potential role for early remodeling in atrial fibrillation[J].Cell Calcium,2006,39(2):175-186.