补肺益肾膏对慢性阻塞性肺疾病稳定期患者生活质量影响的评价研究

Clinical Study on the Effects of Bufei Yishen Treatment on Quality of Life of Patients with Chronic Obstructive Pulmonary Disease in Stable Period

目的观察补肺益肾膏对慢性阻塞性肺疾病稳定期患者生活质量的影响。方法将64例患者随机分为2组,对照组(32例)予异丙托溴铵气雾剂吸入及沐舒坦口服治疗,治疗组(32例)在对照组用药基础上加用补肺益肾膏治疗,3个月为1个疗程。主要观察治疗前后中医证候和主症积分、生活质量评分及肺功能测定结果的变化。结果治疗组治疗后中医证候、主症积分及生活质量评分明显优于对照组(P < 0.05),肺功能测定结果无明显变化(P > 0.05)结论补肺益肾法对慢性阻塞性肺疾病稳定期患者生活质量确有疗效。

Objective To observe the clinical effects of Bufei Yishen treatment on quality of life of patients with chronic obstructive pulmonary disease in stable period. Methods Sixty-four patients were randomly divided into two groups, the control group （32 cases） received Atrovent metered dose inhaling and Mucosolvan po. The treatment group {32 cases） received the fluid extract of Bufei Yishen besides the routine treatment. Both groups were treated for three months. The changes of scores of TCM syndrome and cardinal symptom, quality of life （QOL）, lung function were observed before and after the treatment. Results The scores of TCM syndrome and cardinal symptom, quality of life of the treatment group were significantly higher than the control group （P〈0.05）, though the change of lung function was not obvious （P 〉0.05）. Condusion Bufei Yishen treatment has significantly effect on quality of life of patients with chronic obstructive pulmonary disease in stable period.