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小鼠表皮生长因子对人胚眼角膜上皮组织增殖效应的研究

THE EFFECT OF MOUSE EPIDERMAL GROWTH FACTOR ON CELL PROLIFERATION OF CORNEAL EPITHELIUM OF HUMAN EMBRYONIC EYES
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摘要 报道了人胚眼角膜上皮组织离体培养试验,结果表明,小鼠颌下腺表皮生长因子,对离体培养人胚眼角膜上皮组织,具有明显促进细胞增殖和分化的效应。培养4d的实验组角膜上皮组织厚度、上皮细胞增殖层数以及角膜上皮表层细胞核数量,均较正常人胚角膜上皮组织增长2倍。角膜上皮组织结构中基底细胞核数与表层细胞核数的比率较正常人胚角膜上皮组织增长3倍。 In vitro culture of corneal epithelium of human embryonic eyes indicated that there was an obvious effect of cells proliferation and differentiation of the corneal epithelium of human embryonic eyes induced by epidermal growth factor of mouse submaxillary gland.After 4 days culture in vitro.The tickness of corneal epithelium,the cell layers of epithelium and numbers of nuclei of surface layer cells in corneal epithelium increased two times than that of the corneal epithelium of normal embryonic eyes,the ratio between the nuclei number of basement layer cells and the nuclei number of surface lager cells increased three times than that of the corneal epithelium of normal human embryonic eyes.
出处 《江西科学》 1998年第1期31-34,共4页 Jiangxi Science
关键词 表皮生长因子 胚胎 角膜 上皮组织 增殖效应 Epidermal growth factor(EGF),Human embryo,Corneal epithelium.
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