卒中后尿失禁对卒中患者1年生存的影响

Effect of poststroke urinary incontinence on one year survival of stroke survivors

目的评估卒中后尿失禁(UI)对患者1年生存率的影响。方法前瞻性连续收集急性患者130例,按发病1～10 d(病初)有无UI分为2组,比较2组的基线特征、1年生存率,经多因素分析了解UI的危险因素以及UI与卒中1年生存率的关系。结果UI组的全前循环综合征例数和国立卫生研究院卒中量表(NIHSS)评分显著高于非UI组(P=0.000),与病初UI显著相关(OR=4.52;OR=7.15);UI组41例死亡21例,非UI组89例死亡3例,1年生存率分别为48.8%和96.6%,差异有显著统计学意义(χ2=50.28,P=0.000);病初UI是1年生存的独立危险因素(RR=21.74,P=0.000),患者年龄也与1年生存相关(RR=2.23,P=0.016)。结论病初UI是卒中患者1年生存的强力负性因素,需要加强治疗干预研究。

Objective To evaluate effect of poststroke urinary incontinence （UI） on 1 year survival of stroke survivors. Methods 130 consecutive patients with stroke were collected prospectively and classified as 2 groups by continence status at 1 - 10 days after onset. The patients＇ baseline characteristics and 1 year survival rate were compared. To understand risk factors of UI and correlation between UI and the 1 year survival by multivariate analyses. Results Patients with total anterior circulation syndrome （ TACS ） and NIHSS score in UI group exceeded significantly that in non-UI group （ P = 0. 000） , and associated with initial UI （OR =4. 52; OR =7. 15） . 21 patients died in UI group 41 patients, 3 patients died in non-UI group 89 patients, 1 year survival rate of the 2 groups was 48.8% and 96. 6% respectively, and statistical significance of 2 group difference was significant （ X2 = 50. 28, P = 0. 000） . The initial UI was a independent risk factor to 1 year survival of stroke （RR = 21.74, P = 0. 000）, besides the patients＇ age （ RR =2. 23, P =0. 016） . Conclusions The initial UI might be a strong passive factor to one year surviv- al of the patients with stroke, and should be paid more attention to its intervention studies.