摘要
目的探讨心型脂肪酸结合蛋白(HFABP)对急性冠脉综合征(ACS)的诊断价值。方法采用前瞻性研究方法对115例发病≤6h的ACS患者急诊入院即刻使用CardioDetect试剂盒进行HFABP的定性检测。结果在急性心肌梗死患者中HFABP的检测灵敏度为84.7%,特异度为85.7%,阳性似然比为5.932,阴性似然比为0.178,符合率为85.2%,Kappa值为0.704;在非ST段抬高的心肌梗死患者中HFABP的检测灵敏度为100.0%,特异度为55.3%,阳性似然比为2.240,阴性似然比为0,符合率为60.0%,Kappa值为0.205。结论HFABP的定性检测对早期诊断ACS有一定临床意义。
Objective To evaluate diagnostic value of heart - type fatty acid binding protein （HFABP） in acute coronary syndrome （ACS） and its Clinical classification guidance. Methods A qualitative detection was performed prospectively, instantly using CardioDetect kit, on HFABP ACS patients in 115 ACS patients （chest pain lasting ≤6 h before admission）. Results The HFABP detection sensitivity, specificity, positive likelihood ratio, negative, coincidence, Kappa value were 84. 7%, 85.7%, 5.932, 0. 178, 85.2%, 0. 704, respectively, in patients with acute myocardial infarction, and 100.0%, 55.3%, 2. 240, 0, 60.0%, 0. 205, respectively, in angina pectoris patients. Conclusion Qualitative detection of HFABP is of some clinical significance in early diagnosis and treatment of ACS.
出处
《中国全科医学》
CAS
CSCD
北大核心
2009年第24期2253-2254,共2页
Chinese General Practice
关键词
心型脂肪酸结合蛋白
急性冠脉综合征
急性心肌梗死
早期诊断
Heart fatty acid binding protein
Acute coronary syndrome
Acute myocardial infarction
Early diagnosis
