摘要
观察了有机锗化合物枸橼酸锗对小鼠移植性肿瘤S(180)、H(22)和P(388)的抗肿瘤作用。结果表明，枸橼酸锗0．2、0．4g／kg体重灌胃给药，对小鼠S(180)的平均抑瘤率为47.62％和52.38％；对小鼠H(22)的平均抑瘤率为46.15％和52．20％；对P(388)小鼠生命延长率为24．42％和30．18％，均优于对照组。
The antitumor effect of germanium citrate on transplanted tumor sarcoma(180), H22 and P388 ofmice was observed. Germanium citrate 0. 2 g/kg and 0. 4 g/kg was administrated orally in face respectively. The results showed that its average inhibitory rates to sarcoma(180) were 47 .62 % and 52.38 % , t0Hep(22) were 46. 15 % and 52.20 %. Prolonging rate of the survival time was 24.42 % and 30. 18 % tomice with P(388). The results indicate germanium citrate had an antitumor effect.
出处
《广东微量元素科学》
CAS
1998年第7期44-46,共3页
Trace Elements Science
关键词
枸橼酸锗
抗肿瘤作用
有机锗化合物
Germanium citrate, Antitumor effect, Transplatation tumor in mice
