Logistic回归分析影响急诊手术切口愈合的危险因素

Risk factors of incision healing in emergency operation by Logistic regression analysis

目的研究影响手术切VI愈合的多种危险因素。方法对2008—12～2009—08住院急诊手术患者的临床资料进行统计分析及二分变量Logistic逐步回归分析，筛选出相关因素。结果112例急诊手术患者中，36例发生切口感染或脂肪液化。单因素分析出13个变量中有8个与术后愈合不良有关（P〈0．10）。将8个变量引入二分变量Logistic逐步回归分析模型，筛选出4个相关因素，即合并慢性病（OR=3．764，P=0．014）、手术切口类型（OR=3．148，P=0．031）、输血（OR=4．138，P=0．013）、术中应用生长因子（OR=0．206，P=0．026）。结论合并慢性病、手术切口类型、输血、术中应用生长因子为影响切口愈合的相关因素，治疗慢性病、术中使用生长因子有利于切口愈合。

Objective To study the risk factors of incision healing. Methods The clinical data of hospitalized patients who underwent emergency operation from Dec. 2008 to Aug. 2009 were collected and analyzed by binary Logistic regression analysis in order to sift correlation factors. Results There were 36 cases with incision infection or fat coltiquation in 112 cases. 8 variables had significantly statistical differences by single factor analysis （P 〈 0.10） , in which 4 variables had significantly statistical differences by binary Logistic regression analysis. Conclusion Chronic disease （ OR = 3. 764, P = 0.014）, surgical incision types （ OR = 3. 148, P = 0.031 ）, blood transfusion （OR = 4. 138, P = 0. 013） , growth factor application （ OR =0.206, P =0.026） were correlation factors of wound healing. Chronic disease therapy and growth factor application were beneficial to wound healing.