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凋亡抑制蛋白Apollon与肿瘤的相关性 被引量：1

Relation between inhibitor of apoptosis protein Apollon and tumor
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摘要 Apollon是凋亡抑制蛋白家族的一员，能与Smac、HtrA2及caspase相互作用抑制细胞凋亡.Apollon在白血病、乳腺癌、脑瘤、日腔癌及胃癌等肿瘤中高表达，可能与肿瘤的发生与预后有关，并且可能导致某些肿瘤的耐药。 Apollon is a member of inhibitor of apoptosis proteins. It can inhibit apoptosis through interaction with Stoat, HtrA2 and caspase. Apollon is highly expressed in a variety of tumors, such as leukemia, breast cancer, brain cancer, carcinoma of mouth and carcinoma of stomach. Apollon may relate with genesis and prognosis of tumor. It also may lead to drug resistance of certain tumors.
作者 刘媛媛(综述) 贾秀红(审校)
机构地区 滨州医学院附属医院儿科
出处 《国际肿瘤学杂志》 CAS 2009年第11期833-836,共4页 Journal of International Oncology
关键词 APOLLON 肿瘤 凋亡抑制蛋白类 Apollon Neoplasms inhibitor of apoptosis proteins
分类号 R963 [医药卫生—微生物与生化药学] R730.53 [医药卫生—肿瘤]
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参考文献15

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二级参考文献18

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国际肿瘤学杂志
2009年 第11期

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