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通痹合剂2号对胶原诱导型关节炎大鼠滑膜组织病理的影响 被引量:3

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摘要 目的:研究通痹合剂2号对胶原诱导型关节炎(CIA)模型大鼠滑膜组织病理的影响。方法:滑膜组织常规脱水、包埋、制片、苏木精伊红染色,观察大鼠的滑膜组织病理分级积分情况,以此来判断通痹合剂2号对CIA滑膜组织病理的影响。结果:通痹灵对CIA大鼠滑膜组织的滑膜血管增生、炎症细胞浸润、滑膜细胞增殖有明显抑制作用。滑膜病理总积分与模型组比较,差异非常显著性(P<0.001)。结论:通痹合剂2号能有效抑制类风湿关节炎的滑膜炎症,阻断"滑膜—软骨"这一病理环节。
出处 《光明中医》 2009年第12期2263-2265,共3页 GUANGMING JOURNAL OF CHINESE MEDICINE
基金 广东省自然科学基金博士启动项目(No:06300031)
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