黑龙江省成年女性体脂百分比及腰臀比与心血管功能的关系

The relationship between percentage body fat, waist-hip ratio and cardiovascular function in the adult females of Heilongjiang province

目的 分析黑龙江省成年女性身体脂肪的含量及分布对心血管系统功能的影响。方法依据分层不等概率二阶整群抽样原则，抽取黑龙江省部分地区18—70岁成年女性1903名，测量其身高、体重、腰臀比（WHR）等指标；分析脂肪体重、瘦体重和体脂百分比（PBF）等身体成分指标与心率、心输出量、心指数、搏出量、搏出指数、收缩压、舒张压、左心作功和体循环血管阻力等心血管功能指标的关系。结果女性PBF和WHR有随年龄增长而增大的趋势。18岁-、30岁～、40岁-、50岁～、60～70岁年龄组PBF分别为（16．86±5．37）％、（18．43±4．89）％、（20．99±5．79）％、（23．47±5．74）％、（25．77±6．38）％（F=154．46，P〈0．01），WHR分别为0．77±0．05、0．80±0．05、0．83±0．05、0．85±0．06、0．89±0．07（F=229．84，P〈0．01）。在校正年龄、身高和体重的影响后，PBF正常组心率、心输出量、心指数、收缩压、舒张压、左心作功分别为（75．45±0．35）次／min、（4．42±0．02）L／min、（2．78±0．01）L·min^-1·m^-2、（114．94±0．40）mmHg（1mmHg=0．133kPa）、（64．90±0．28）mmHg、（4．57±0．03）kg·m／m^2，PBF肥胖组分别为（77．42±0．88）次／min、（4．54±0．05）L／min、（2．88±0．03）L·min^-1·m^-2、（120．55±1．00）mmHg、（66．56±0．71）mmHg、（4．86±0．07）kg·m／m^2（两组比较，F值分别为3．18、9．17、8．48、13．50、2．64、10．63，P值均〈0．05）。在校正年龄、身高和体重因素后，PBF与心率、心输出量、心指数、收缩压及左心作功呈正相关（r值分别为0．14、0．14、0．19、0．18、0．10、0．12，P值均〈0．05）；WHR与心指数、搏出指数、收缩压、舒张压、左心作功和体循环血管阻力呈正相关（r值分别为0．10、0．19、0．18、0．12、0．12，P值均〈0．01）。结论女性PBF增加且呈腹部型肥胖者，可导致心脏负荷加重，心输出量增加、血压明显升高等心血管系统功能的改变。

Objective To analyze the relationship between body fat mass and distribution and cardiovascular function in the adult females of Heilongjiang province. Methods Based on the statistic variable random sampling principal ,we selected 1903 healthy adult females with ages of 18 -70 years old in Heilongjiang province to conduct the study. The height, body weight, waist, chest measurement and waist-hip ratio （WHR） were measured. Body components quota including fat weight, lean weight, percentage of body fat （PBF） were taken respectively; systolic blood pressure （SBP）, diastolic blood pressure （DBP）, heart rate （ HR）, cardiac output （ CO）, cardiac index （ CI）, stroke volume （ SV）, stroke index （ SI）, left cardiac work （LCW） and systemic vascular resistance （SVR） were determined. Results The PBF and WHR increased with aging,and the PBF of those with ages of 18 - ,30 - ,40 - ,50 - and 60 -70 year＇s old were （16.86±5.37）%,（18.43±4.89）%,（20.99±5.79）%,（23.47±5.74）% and（25.77 ±6.38）%, respectively （ F = 154.46, P 〈 0.01 ） ; and the WHR were 0. 77 ± 0. 05,0. 80 ±0.05,0. 83 ±0. 05,0. 85 ± 0.06 and 0. 89 ± 0. 07, respectively （ F = 229. 84, P 〈 0. 01 ）. The HR, CO, CI, SBP, DBP and LCW were（75.45±0.35）bpm,（4.42±0.02）L/min,（2.78 ±0. 01）L min^-1 m^-2,（114.94-±0.40）mm Hg （ 1 mm Hg = 0. 133 kPa）, （ 64. 90± 0. 28） mm Hg, （4. 57 ± 0. 03 ） kg· m/m2 respectively in normal PBF groups ; whereas the HR, CO, CI, SBP, DBP and LCW in the PBF obesity groups were （ 77.42 ± 0. 88 ） bpm, （4.54±0.05） L/min , （ 2. 88±0. 03 ） L- min^-1 m^-2,（120.55±1.00） mm Hg,（66.56±0.71） mm Hg and （4. 86 ± 0. 07 ） kg · m^2 , respectively, F values were 3. 182,9. 173,8. 478, 13. 497,2. 637, and 10. 631, respectively （all P values 〈 0. 05 ） after the adjustment of age, height and weight, PBF was positively correlated with HR, CO, CI, SI, SBP, DBP and LCW （ r values were 0. 06,0. 11 , 0. 10,0. 11 and 0. 12, respectively,all P values 〈 0. 05 ） ; WHR was positively correlated with CI, SI, SBP, DBP, LCW and SVR （ r values were 0. 14,014,0. 19,0. 18,0. 10 and 0. 12, respectively, all P values 〈 0. 01 ） after the adjustment of age, height and weight. Conclusion PBF augmentation and abdominal obesity in females can result in cardiac dysfunction such as cardiac overload, CO increasing and blood pressure rising.