珠江口水域细菌抗药性的研究

Study on antibiotics resistance of bacteria in Pearl River Estuary

为了解珠江口水域细菌耐药性分布情况,将海水中细菌分离鉴定并进行细菌药敏实验。结果检出细菌22种120株,检测得120株细菌的抗生素谱,具有较高细菌耐药性的抗生素为:青霉素G耐药菌株的百分比为43.30%、氨苄青霉素AM的为51.70%、头孢唑啉CI的为44.20%、卡那霉素K的为46.70%、阿米卡星AN的为50.80%、新生霉素NOV的为60.00%、四环素TE的为60.80%、复方新诺明SX的为43.30%。细菌对链霉素S、诺氟沙星NOR、氯霉素C、环丙沙星CIP的耐药性比较低,分别为16.70%、16.70%、14.20%、13.30%。本实验对海洋微生物的研究、抗生素的安全使用以及环境保护均具有一定的指导意义。

The investigation of the distribution and their antibiotic resistance of bacteria isolated from the Pearl estuarine of South China Sea were carried out. The identification was done by means of API stripes. The antibiotic sensitivity test was done by K-B method. The results showed that 43.30% bacteria were the resistant to penicillin,51.70% to ampicillin,44.20% to cefazolin ,46.70% to kanamyein,50.80% to amikacin ,60. 00% to novobioein,60.80% to tetracycline,43.20% to trimethoprim ＋ sulfamethoxazole, 16.70% to streptomycin, 16.70% to norfloxacin, 14.20% to chloramphenicol and 13.30% ciprofloxacin. This investigation will be helpful for the research of the marine microorganism and environmental protection.