小麦纤维素颗粒治疗中国南方功能性便秘患者的有效性与安全性

Wheat bran on the treatment of functional constipation patients in South China

目的观察小麦纤维素颗粒对中国南方功能性便秘患者的疗效及安全性。方法采用随机自身对照研究的方法,对100例采用传统中国南方食谱的功能性便秘患者进行研究,给予小麦纤维素颗粒连续治疗14d,观察患者服药前后便秘症状及粪便性状的改变,并对其进行评分量化比较。结果应用小麦纤维素颗粒治疗后第7天、第14天的便秘症状和粪便性状与治疗前相比较,各项症状的评分均显著下降,差异有统计学意义(P<0.05)。服药期间未发现腹痛、腹胀等不良反应。结论对采用中国南方饮食的功能性便秘患者,小麦纤维素颗粒是一种安全有效的良好药物。

Objictive To investigated the efficacy and safety of wheat kernel on the treatment of patients with functional constipation in South China.Methods 100 cases of functional constipation patients （with traditional food of South China） were conducted with wheat kernel （Fiberform） continually for 14 days.Symptoms and the properties of feces before and after the treatment were observed and evaluated according to a measuring scale.Results Frequency of defecation increased significantly and the character of the feces was improved after the treatment （ P 〈 0.05 ）. No abdominal pain or abdominal distention was observed during the treatment. Conclusion Wheat kernel was an effective and safety choice for patients with functional constipation patients with traditional food of South China.