3[17]Lu QL,Liang HD,Partridge T,et al.Microbubble ultrasound improves the efficiency of gene transduction in skeletal muscle in vivo with reduced tissue damage.Gene Therapy,2003,10:396-405.
5[2]Levy MY,Barron LG,Meyer KB,et al.Characterization of plasmid DNA transfer into mouse skeletal muscle:evaluation of uptake mechanism,expression and secretion of gene products into blood.Gene Ther,1996,3:201-211.
6[3]Russell SJ.Science,medicine,and the future-gene therapy.British Medical Journal,1997,315:1289-1292.
7[4]Chao H,Walsh CE.Novel method for human factor Ⅷ packaging and expression:dimerization of rAAV vectors.Blood,2000,96:924.
8[5]Hagstrom JN,Couto LB,Scallan C,et al.Improved muscle-derived expression of human coagulation factor Ⅸ from a skeletal actin/CMV hybrid enhancer/promoter.Blood,2000,95:2536-2542.
10[7]Nakai H,Storm TA,Kay MA.Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors.Nature Biotechnology,2000,18:527-532.