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颈动脉狭窄与失语症发病关系的临床研究

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摘要 目的通过检测颅内外血管狭窄程度,探讨颈动脉狭窄与失语症发病的关系,推测失语症可能的发病机制,为临床选择实施治疗方案提供客观依据。方法对10例脑梗死失语症且经头颅CT或MRI证实为左侧半球病变的患者,均行北京医科大学第一附属医院汉语失语成套测验中的亚项利手评定和判断失语症类型,采用Frenchy构音障碍评定标准进行构音障碍评定。并对颅内外血管的血流速度进行分析。结果10例患者利手评定均为右利手,8例运动性失语,1例感觉性失语,1例混合性失语。Frenchy构音障碍评定均无构音障碍。超声检查8例患者左侧颈内动脉中-重度狭窄或闭塞.颅内动脉处于低灌注状态;1例左侧大脑中动脉重度狭窄;1例左侧颈内动脉窦部斑块形成。10例患者中5例行全脑数字减影血管造影(DSA),结果与经颅多普勒、颈动脉超声检查结果一致。结论颈动脉系统中-重度狭窄或闭塞,使颅内动脉灌注压下降,狭窄远端血流速度减低,语青中枢的低血流灌注可能为失语症的发病机制。
出处 《中国医师进修杂志(内科版)》 2009年第12期57-59,共3页 Chinese Journal of Postgraduates of Medicine
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