紫荆叶对模型小鼠的消炎镇痛及耐缺氧抗疲劳作用研究

Anti-inflammatory,Analgesic,Anti-hypoxia and Anti-fatigue Effect of Cercis chinensis Leaf on Model Mice

目的:研究紫荆叶对模型小鼠消炎、镇痛及耐缺氧、抗疲劳的作用。方法:以二甲苯法和扭体法研究紫荆叶的醇提物及水提物的消炎镇痛作用,以游泳和耐缺氧实验研究紫荆叶醇提物及水提物的耐缺氧、抗疲劳作用。结果:紫荆叶醇提物较水提物具有更加显著的镇痛、消炎作用;水提物较醇提物更能显著增强小鼠耐缺氧和抗疲劳的能力。结论:紫荆叶具有显著镇痛、消炎作用,并能增强小鼠耐缺氧和抗疲劳的能力,且呈剂量-效应关系。

OBJECTIVE： To study the anti - inflammatory, analgesic, anti - hypoxia, and anti - fatigue effects of the Cercis chinensis leaf on model mice. METHODS： The anti - inflammatory and analgesic effects of the alcohol extract and water extract of C. chinensis leaf were studied by dimethyl benzene method and writhing method, and their anti - hypoxia and anti - fatigue effects were evaluated through swimming test and hypoxia tolerance experiment. RESULTS： Compared with the water extract, the alcohol extract of the C. chinensis leaf showed more remarkable anti- inflammatory and analgesic effects, however, the water extract showed more remarkable anti- hypoxia and anti- fatigue effects than the alcohol extract .CONCLUSION： The C. chinensis leaf had remarkable anti- inflammatory, analgesic, anti- fatigue and anti- hypoxia effects in dose - dependent manner.