摘要
Dear Editor, Parkinson＇s disease （PD） is the second most common neurodegenerative disease after Alzheimer＇s disease （AD）. Although treatments for PD may be beneficial in the early stages of disease, accurate diagnosis during these stages remains a challenge. An ideal diagnosis for PD should be highly specific and sensitive, as well as be able to predict disease progression. Currently, diagnosis of PD relies mainly on the evaluation of clinical features, specifically cardinal signs.
基金
This work was supported by grants from the Chinese Ministry of Science ＆ Technology （No. 2004AA221130）, the Shanghai Metropolitan Fund for Research and Development （No. 07DJ14005）, the National Natural Science Foundation of China （Nos. 30525041, 30721004）, and the State Key Program for Basic Research of China （No. 2006CB500704）.
