钩虫等土源性线虫病防治试点10年纵向观察

A TEN-YEAR LONGITUDINAL OBSERVATION ON THE CONTROLOF HOOKWORM AND OTHER SOILTRANSMITTEDNEMATODIASIS IN THE STUDY SITE

为了得出适合中国东南部阻断钩虫等土源性线虫病传播的措施，１９８６～１９８８年对钩虫、蛔虫和鞭虫卵阳性者采用阿苯达唑每年治疗２次，连续化疗两年，使钩虫、蛔虫和鞭虫的感染率分别自５２．３％、６０．３％和２８．３％下降至３．２％、３７．３％和３．５％；１９８９～１９９２年采取重点人群（指１９８８年钩虫卵阳性者和历年漏治者）治疗，钩虫感染率继续下降到０．５％；１９９３～１９９６年不采取任何干预措施，钩虫感染率维持在０．５％左右，土壤中分离不到钩蚴。人群血红蛋白水平逐年提高。

The objective of the project was to search for suitable measures to control the infection of hookworm and other soil-transmitted nematodiasis in the southeast part of China. The prevalence rates of hookworm,Ascaris and whipworm decreased from 52.3%, 60.3% and 28.3% to 3.2%, 37.3% and 3.5% respectively, after administration of albendazole twice a year for 2 years in 1986-1988. In 1989-1992, the prevalence rate of hookworm continued to decrease to 0.5%, when treatment was carried out in the people who were eggpositive in 1988 or who missed chemotherapy in the previous years. During 1993-1996, no preventive measures were taken,while the infection rate of hookworm remained about 0.5%. Hookworm larvae werent isolated from soil. The mean hemoglobin levels of sampled populations increased after treatment. The above data showed that hookworm transmission was basically controlled in the study site.