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2型糖尿病男性患者骨量变化相关因素分析

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摘要 目的:探讨2型糖尿病(T_2DM)男性患者骨量的变化及其关联因素。方法:对2008年2月~2009年2月入住我科的40~70岁男性T_2DM患者腰椎和股骨近端BMD、血糖、HbAlc、胰岛素、血脂进行检测,随机选取30例骨质正常作为对照组与骨质疏松组、骨质减少组进行比较。结果:与骨质正常组相比,骨质疏松组和骨质减少组腰椎和股骨近端BMD明显降低(P<0.01),以Neck、Ward's三角区最明显,空腹和餐后2h胰岛素明显降低(P<0.01)。腰椎和股骨近端BMD与BMI、2hlns呈正相关,与HbAlc呈负相关。结论:Neck、Ward's三角区可作为T_2DM男性患者早骨量丢失观察的重要部位,其腰椎和股骨近端骨量变化与胰岛素、C肽水平密切相关,高BMI和良好的血糖控制可减少骨量丢失。
出处 《新疆医学》 2009年第10期1-3,共3页 Xinjiang Medical Journal
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