腹腔镜脾切除术治疗特发性血小板减少性紫癜的临床应用

Clinical application of laparoscopic splenectomy for idiopathic thrombocytopenic purpura

目的探讨腹腔镜脾切除术（1aparoscopics plenectomy，LS）治疗特发性血小板减少性紫癜（idiopathic thrombocytopenic purpura，ITP）的可行性及临床疗效。方法回顾性分析2007年10月至2009年2月间16例行LS治疗ITP的临床资料。结果本组治愈15例，无再发出血，血小板总数上升为（130-439．1）×10^9／L；部分有效1例。术后并发肺部感染1例，戳孔感染2例，发热2例，均行对症治疗后治愈。术后无死亡病例。随访4～12个月．无复发病例。结论LS治疗ITP是安全、可行的。疗效良好。

Objective To explore the safety and efficacy of laparoscopic spleneetomy（LS）for idiopathic thrombocytopenic purpura（ITP）. Methods The clinical data of 16 patients with ITP undergoing LS from Oct. 2007 to Feb. 2009 were analyzed retrospectively. Results Fifteen patients got recovery, their platelet counts were elevated rapidly（ range from 130 × 10^9/L to 439. 1 × 10^9/L）, and there was no re-bleeding post-operatively. One patient got partial recovery. Postoperative complications occurred in 5 cases including, one case of lung infection,2 case of fever. After the symptomatic treatment 5 cases got recovery successively and no case died. Conclusion LS is a relatively safe and effective measure for treatment of ITP.