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RASSF1A基因启动子甲基化与肿瘤关系的研究进展 被引量：1

Research Progression of RASSF1A and primary tumor tissue
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摘要 RASSF1A是一个位于3p21.3染色体上的抑癌基因。该基因在多种肿瘤的细胞系和原发肿瘤组织中的失活是很普遍的。RASSF1A基因启动子甲基化可能是肿瘤发生的早期事件并可能做为早期诊断的重要分子标志。 Ras association domain family 1 agene （ RASSF1 A ） is transcript A of gene RASSF1, a tumor suppressor gene located at 3p21.3. Promoter hypermethylation of RASSF1A and inactivation of RASSF1A are very popular in many tumor cell line and primary tumor tissue. It may be an early event in the development of tumors and could be used as important molecular maker in early diagnosis.
作者 任涛 李锋
机构地区 石河子大学医学院 石河子大学医学院病理学教研室
出处 《农垦医学》 2009年第5期441-444,共4页 Journal of Nongken Medicine
基金 973前期专项 教育部科学研究重大项目(No.2007CB516804) 教育部高校创新工程重大项目培育资金项目(206167) 国家科技支撑计划(No.2009BAI8200)
关键词 RASSF1A 甲基化 肿瘤 RASSF1A Methylation Tumor
分类号 Q754 [生物学—分子生物学]
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农垦医学
2009年 第5期

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