突发性耳聋52例临床分析

Clinical analysis on 52 cases with sudden deafness.

目的探讨影响突发性耳聋治疗效果的临床因素和预后情况。方法对1年内我院收治的52例(53耳)突发性耳聋患者的临床资料采用fisher检验进行统计分析。结果发病时间越短,不伴眩晕症者,治疗效果越好(P<0.05);早期足够疗程高压氧干预可明显提高疗效(总有效率66.67%);发病年龄与疗效无相关性(P>0.05)。结论影响突发性耳聋疗效因素众多,基本治疗方案是改善内耳微循环,降纤药物,激素及营养神经药物的应用,但应强调早期治疗,高压氧疗干预可明显提高疗效。

Objective To study the clinical factors influencing the efficacy of treatment and prognosis of patients with sudden deafness. Methods Analysis on clinical data of 52 patients with sudden deafness treated in this hospital within 1 year was carried out and their results were statistically analyzed by Fisher test. Results Patients with shorter duration of onset of the disease without vertigo could have better effect of treatment （ P 〈 0.05 ）. The early treatment with hyperbaric oxygen could significantly raise the curative effect （the total effective rate was 66.67% ）. There was no relationship between age of onset and effectiveness （ P 〉 0.05 ）. Conclusion There are many factors affecting the therapeutic effect of sudden deafness, the basic treatment regimen is improving the microcirculation of inner ear including application of drugs for reducing fibrosis, hormones and neurotrophic drugs, especially applied in early stage of the disease. The hyperbaric oxygen treatment could significantly inevease curative effect of the disease.