肺动脉血流时间间期法评估肺动脉压

Validation of Doppler-Derived Pulmonary Flow Time Intervals in Estimating Pulmonary Arterial Pressures

为评价肺动脉血流时间间期法评估肺动脉压的价值,本文观察了37例左向右分流先天性心脏病患者。在相同体位及取样容积位置下测量心室射血前期(PEP)、射血时间(ET)、加速时间(AT)、加速度(ACC)、F[F=PEP/(ATET)];计算肺动脉/主动脉血流时间间期比(FPA/FAO),并以各项比例系数与肱动脉压(BAP)的乘积作为肺动脉压的估测值。结果显示:肺动脉/主动脉血流时间间期比与右心导管估测的肺动脉收缩压(PASP)、平均压(PAMP)取得了较好的相关性(r分别为0.84、0.81);ACC次之(r分别为0.72、0.65);PEP/AT较差(r分别为0.53、0.50)。提示:肺动脉/主动脉血流时间间期比为无创定量评估肺动脉压的最佳方法。

TO assess the accuracy of Doppler Echocardiography for prediating the pressure of pulmonary (PAP), we studied 37 children with a left -to -right heart catheterization. Recordings of preelection (ACC) were made by Doppler echocardiography in the same body position and the same sample volume to calculate PEP/AT,ACC,FPA/FAO[F = PEP/(AT * ET)],the estimatied PAP were defined as the products of the radios and the brachial arterial pressure measured by a cuff sphy-gomomanomenter. The results showed that the best correlations with pulmonary arterial systolic and mean pressure (PASP.PAMP) were obtained by the EPA/FAO(r = 0. 84,0. 81) ,the ACC correlated well with PASP, PASP(r = 0. 72,0. 65),the correlations between PEP/AT and PASP.PAMP were not so good as those between ACC and FPA/FAO(r=0. 53,0. 50). Thus,FPA/FAO is a new accurate parameter for quantitative assessment of PAP.