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血浆NT-proBNP在舒张性心力衰竭疗效评价中的意义 被引量:6

The meaning of plasma NT-proBNP in evaluating the effect of diastolic heart failure therapy
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摘要 目的探讨血浆NT-proBNP在舒张性心力衰竭治疗中的意义。方法设置舒张性心功能衰竭组(DHF患者37例)和对照组(健康体检者12例),分别测定和比较两组血浆NT-proBNP值;比较舒张性心功能衰竭组各级心功不全者NT-proBNP值。结果心衰组血浆NT-proBNP水平显著高于对照组,且随着心功能分级升高而升高。结论NT-proBNP可作为DHF疗效评价的指标之一。 OBJECTIVE To investigate the meaning of plasma NT-proBNP in evaluating the effect of diastolic heart failure therapy.METHODS There were two groups:the DHF group (37 cases of DHF patients) and control group (12 cases of healthy persons).The value of plasma NT-proBNP of the two groups was measured and compared,as well as in DHF group at all levels of heart failure.RESULTS The value of plasma NT-proBNP increased with the level of heart failure.CONCLUSION NT-proBNP could be used as one of the indicators of DHF.
出处 《海峡药学》 2009年第11期133-135,共3页 Strait Pharmaceutical Journal
关键词 N-末端脑钠肽前体 舒张性心力衰竭 NT-proBNP Diastolic heart failure
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  • 1Vasan RS, Levy D. Defining diastolic heart failure:a call for standardized diagnostic criteria (J). Circulation, 2000, 101(17) : 2118-2121.
  • 2Mukayama M, Nakao K et al. Increased human barin natriuertic pepetide in congestive heart filuer[J].N Engl J Med, 1990, 323(11) :757.
  • 3Lubien E, DeMaria Aet al. Utiliy of B-natriuertie peptide indetecting diastolic dysfunction:comparison with Doppler velocity recordings [J]. Circulation, 2002, 105(5) : 595-601.
  • 4Krishnaswamy P, Lubien E, et al. Utifity of B-natriuretic peptide levels in identifying patients with left ventricular systolic or diastolic dysfunction [J] . Am J Med, 2001,111 (4) : 274-279.

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