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贝那普利治疗慢性稳定型心绞痛的疗效观察

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摘要 目的探讨在常规治疗稳定型心绞痛的基础上,加用贝那普利的疗效。方法93例慢性稳定型心绞痛患者随机分为常规治疗组和贝那普利组,2组均接受常规治疗,贝那普利组加服贝那普利。结果2组治疗后ST段压低幅度、ST段压低持续时间、次极量平板运动实验的运动时间和运动行程较治疗前明显改善(P<0.05),治疗后组间比较,上述指标贝那普利组较常规治疗组改善更明显(P<0.05)。长期随访表明长期治疗能减少心源性死亡、急性心肌梗死、每月心绞痛发作次数及每月硝酸甘油用量(P<0.05)。结论在常规治疗心绞痛基础上,加用贝那普利更能改善冠脉血供及减少缺血相关事件、改善症状及提高患者生活质量。
出处 《海峡药学》 2009年第11期152-153,共2页 Strait Pharmaceutical Journal
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