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高糖对THP-1人单核细胞表达iNOS和IL-1β的影响 被引量：1

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摘要 糖尿病是由多种病因引起的以慢陛高血糖为特征的代谢紊乱。已有的研究结果表明，糖尿病高血糖可以影响单核细胞趋化、粘附作用，促进细胞凋亡。本文在体外培养人单核细胞株（THP-1）的基础上，以高浓度葡萄糖刺激，通过检测细胞表达诱导型一氧化氮合酶（iNOS）和IL-1β的情况，探讨高糖状态下免疫细胞功能的变化。
作者 陈樱 孟东 孙蓓 邓为民 姚智
机构地区 天津医科大学代谢病医院 天津医科大学
出处 《天津医科大学学报》 2009年第4期708-709,共2页 Journal of Tianjin Medical University
基金 天津医科大学科学基金资助项目(2006KY23)
关键词 高糖 单核细胞 INOS IL-1Β
分类号 R392.1 [医药卫生—免疫学]
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参考文献5

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二级参考文献7

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共引文献38

同被引文献10

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天津医科大学学报
2009年 第4期

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