压力-放射性计数曲线在核素显像诊断胃食管返流中的价值

The value of pressure-radio activity curve in radionuclide imaging in diagnosis of gastroesophageal reflux

目的:评价压力-放射性曲线在放射性核素胃食管显像诊断胃食管返流中的应用价值。方法:经其他检测方法确诊为胃食管返流患者76例(X线钡剂检查阳性42例,胃镜检查阳性34例),行常规GES显像,采用三种方法对结果进行判断,即目测法、时间-放射性计数曲线法和压力-放射性计数曲线法,并对结果进行统计学处理。结果:76例患者中,目测组胃食管返流阳性58例,检出率为76.3%;时间-放射性曲线组胃食管返流阳性63例,检出率为82.9%;压力-放射性曲线组胃食管返流阳性69例,检出率为90.8%,与前两者比较,压力-放射性曲线组其GER阳性检出率明显提高(χ2=13.31,P<0.05)。结论:在目前诊断胃食管返流的方法中,放射性核素显像具有简便无创、符合生理状态、动态观测、定量分析、可同时观察胃排空功能等优点,明显提高了阳性检出率。

Objective： To evaluate the value of pressure - radio activity curve （PRAC） in the diagnosis of gastroesophageal reflux （GER） by gastroesophagcal seintiglaphy （GES）. Methods： 76 patients with GER were final diagnosed by other ways in which 42 patients was by X - ray and 34 by gastrescopy. All 76 cases underwent GES from which results were respectively obtained by visualization, time - radio activity curve（ TRAC） and Pressure- radio activity curve （PRAC）, and the data was analyzed by statistics. Results： The positive detection rate were 76.3%, 82.9% and 90.8% by visualization, TRAC and PRAC respectively in 76 patients. Compared with visualization and TRAC, we can see the significant difference in detection rate by PRAC （Χ^2 = 12.48, P 〈 0. 05;Χ^2 = 13. 80, P 〈 0. 05） . Conclusion： In the present diagnosis methods of GER, GES shows the following strong points： convenience non - invasive, consistent with physiological state, dynamic surveying, quantitive analysis, simultaneously observe the gastric emptying, and PRAC can increase remarkably the positive detection rate.