摘要
目的：观察佳苏仑用于全麻术后病人催醒及拮抗呼吸抑制的临床效果。方法：观察３２例全麻病人，持术毕，佳苏仑１－２ｍｇ／ｋｇ用５０％葡萄糖稀释成１０毫升。缓慢静注，必要时１０￣１５分钟后追加半量或全量，观察用药前后病人苏醒情况及病人血压、心率、血氧饱合度。结果：静脉注射佳苏仑后２分钟、６分钟、１０分钟分别有５例、１８例、４例病人达到拔管指征。病人呼吸频率，血氧饱合度同用药前相比有明显改善，（Ｐ〈０．
To observe the clinical effects of Doxapram on awaking and antagonizing respiratory inhibiion after operation with general anesthesia.Method:32 cases of patients with general anesthisa were observed.After operations,1-2mg/lg of Dorxapram,diluted with glucose into 10ml,was injected into the veins slowly.If necessary,half dosage of whole dosage of Foxapram was given again 10 to 15 minutes later.The awaking of the patients was observed before andafter adminstration of Doxapramin.The blood pressure respiration heart rate and bolld oxygen satuation were also examined.Results:2;6 and 10 minutes after intrarvencous injection of Doxapram.5;18 and 4 patients showed the indication of decannulation respectively As compared wiht those before administration,respiratory rate and hlood oxygen saturation were improved significant (P<0.01).It can awaken the patients rapidly after anesthesia and have little imfhiConclosion:Doxapram is a nonspecific stumulant ofrespiration and analeptic(P>0.05).It can awaken the patients raidly after anesthesia and have little influence on beart rate and blood pressure.There is grest significance in clinical application.
