间断无创正压通气联合雾化吸入支气管扩张剂及糖皮质激素治疗AECOPD依从性及疗效分析

Compliances and clinical effect of intermittent non-invasive positive ventilation combining nebulized inhalation with bronchodilator and glucocorticoidin treatment for patients with acute exacerbation of chronic obstructive pulmonary disease

目的探讨间断无创正压通气(NIPPV)联合雾化吸入治疗AECOPD的临床疗效。方法选择入院AECOPD患者随机分为治疗组和对照组各30例,治疗组使用氧动雾化器吸入气管扩张剂及糖皮质激素后使用NIPPV。根据情况可反复交替,观察组单纯使用NIPPV,观察两组的依从性、气管插管率、带机时间、住院时间。结果治疗组各项指标均优于对照组(P<0.05)。结论间断NIPPV联合雾化吸入气管扩张剂及糖皮质激素疗效显著。

Objective To evaluate the value of intermittent non-invasive positive pressure ventilation combining nebulized inhalation in the treatment of acute exacerbation of chronic obstructive pulmonary disease （AECOPD）. Methods Patients with AECOPD were randomly divided into trial group（ 30 cases）and control group（ 30 cases）. The trial group inhaled bronchodilator and glucocorticoid by oxygen nebulization and then used NIPPV in turn repeatedly according to the situation. The control group used NIPPV only. Two groups of compliances, the trachea cannala rate,ventilation time, length of stay in hospital were observed. Results The trial group indicators were better than the control group （ P 〈 0. 05 ）. Conclusion Intermittent NIPPV combined inhalation bronchodilators and glucocorticoid has positive effects on patients with AECOPD.