42例产气肠杆菌肺炎临床分析

Clinical analysis of 42 cases of enterobacter aerogenes pneumonia

目的探讨产气肠杆菌肺炎的临床特点和抗生素敏感的分布;方法对42例产气肠杆菌肺炎的临床资料进行分析,同时以K-B法测定微生物的敏感性;结果≥70岁的患者32例(76.1%);有基础疾病的35例(83.3%),其中有肺基础疾病者18例(42.9%),院内感染22例(52.4%);临床主要表现为咳嗽、咳痰伴有发热18例(42.9%);胸片、CT以片状渗出为主要表现有40例(95.2%);药敏结果显示除对亚胺培南100%敏感,对头孢哌酮-舒巴坦95%敏感,头孢吡肟93%敏感,阿米卡星90%敏感外,对第三代头孢菌素的敏感性也在45%左右;结论产气肠杆菌肺炎好发于老年人,且大都伴有基础疾病,对抗生素敏感性差,应及早选择敏感抗生素以改善预后。

Objective To analyze the clinical features of enterobacter aerogenes pneumonia and the distribution of antibiotic-sensitivity. Methods Clinical data of 42 cases with enterobacter aerogens pneumonia were analyzed and the KB method was used to evaluate the sensitivity of micro-organisms. Results About 76. 1% of the cases were older than or equal to 70 years old. 35 cases （ 83.3 % ） had underlying diseases. Among them, 18 cases （42. 9% ）had basic lung disease and 22 cases （52. 4% ）were nosocomial infected. The main clinical symptoms were cough, expectoration, and 18 cases （42.9%）were accompanied by fever. Chest X-ray and/or CT had flake infiltration as the main manifestation in 40 cases（95.2% ）. Drug susceptibility results indicated 100% sensitive to imipenem, and cefoperazone-sulbactam 95 % sensitive and 93 % of cefepime-sensitive masonry, amikacin 90% sensitive to outside. Sensitivity to the third generation cephalosporins was only 45%. Cnclusion Enterobacter aerogenes pneumonia is usually occurred in the elder, which is accompanied by the underlying diseases. Early selection of the sensitive antibiotics can improve the prognosis.