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内皮抑素的生物活性及作用机制的研究进展 被引量:6

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摘要 抑制血管生成已被证实是遏制肿瘤生长的有效策略,内皮抑素是目前发现的最有效抑制血管生成的物质。内皮抑素是一分子量约为20KD的胶原XVIII羧基末端片段,具有抑制血管内皮细胞增殖、诱导血管内皮细胞凋亡、抑制血管生长因子等抗血管生成作用。内皮抑素对60多种肿瘤有抑制作用,但是具体作用机制尚不明了,本文着重对内皮抑素的生物活性机制做一介绍。
出处 《临床肺科杂志》 2010年第1期64-66,共3页 Journal of Clinical Pulmonary Medicine
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