摘要
为探讨防治肝癌的更有效方法，采用人参、鳖甲、女贞子等补气滋阴中药配成的组方喂养大鼠，观察其对中药组、诱癌组及正常对照组大鼠肝癌的发生率、肝功能及体重的变化。结果中药组癌变率明显低于诱癌组（P＜0．05），中药组较诱癌组肝功能损害程度轻（P＜0．01），各组体重增长以正常对照组最为明显，中药组次之，诱癌组增长不明显，有的甚至下降。提示补气滋阴中药能明显减轻因毒物引起的肝脏损害及抑制二甲基奶油黄诱发大鼠肝癌的发生。
To observe the effects of bettering-qi and nourishing-yin Chinese herbs (group CHconsisting of panax ginseng, amyda sinensis, ligustrum lucieum an,et al) on the rate of liver canceration, liver function and weight in rats, 90 male wistar rats were divided into three groups; rats ingroup CH were fed on forage with DAB and CH, in group IC(induced cancer) on forage with DABonly and in control group on ordinary forage. The results indicated that the rate of liver canceration inCH group was lower than that in iC group(P ＜0. 05),the damage of liver function in CH group wasmilder than that in IC group(P＜0. 01 ). However, the weight gain was the most obvious in controlgroup among the three groups whereas it even dropped in IC group. According to the results, it wasproved that the bettering-qi and nourishing-yin Chinese herbal could reduce liver damage from toxinand inhibit liver carcinogenesis in rats induced by DAB.
关键词
肝肿瘤
二甲基奶油黄
补气滋阴
治疗
hepatocarcinoma, DAB, bettering-qi and nourishing-yin
