硫化砷诱导K562细胞凋亡

Arsenic bisulfide induces apoptosis in K562 cells

研究硫化砷（Ａｓ２Ｓ２）对Ｋ５６２细胞凋亡的诱导作用。采用Ｋ５６２细胞体外培养，应用流式细胞仪（ＦＣＭ）分析细胞周期，鉴定凋亡细胞，检测线粒体膜蛋白Ａｐｏ２７的表达。结果显示：Ａｓ２Ｓ２能够诱导Ｋ５６２细胞凋亡，使细胞周期中的Ｓ期细胞减少，Ｇ２／Ｍ期细胞升高。

To investigate the apoptosis of chronic myelogenous leukemia cells induced by arsenic bisulfide,K562 cells were cultured in vitro.Apoptosis was detected by flow cytometric cell cycle analysis.Apo27 expression was detected by flow cytomctry.Thc results showed that arsenic bisulfide is able to induce K562 cells into apoptosis.