摘要
研究硫化砷(As2S2)对K562细胞凋亡的诱导作用。采用K562细胞体外培养,应用流式细胞仪(FCM)分析细胞周期,鉴定凋亡细胞,检测线粒体膜蛋白Apo27的表达。结果显示:As2S2能够诱导K562细胞凋亡,使细胞周期中的S期细胞减少,G2/M期细胞升高。
To investigate the apoptosis of chronic myelogenous leukemia cells induced by arsenic bisulfide,K562 cells were cultured in vitro.Apoptosis was detected by flow cytometric cell cycle analysis.Apo27 expression was detected by flow cytomctry.Thc results showed that arsenic bisulfide is able to induce K562 cells into apoptosis.
出处
《大连医科大学学报》
CAS
1998年第3期19-20,共2页
Journal of Dalian Medical University