活脑灵治疗脑血管疾病后遗症的疗效

A CLINICAL STUDY WITH BUFLOMEDIL IN TREATMENT OF SEQUELIN CEREBROVASCULAR DISEASE

目的：研究活脑灵治疗脑血管疾病后遗症的临床疗效及安全性。方法：选用３１例确诊为脑血管疾病（包括原发病为脑出血及脑梗塞）后遗症的患者，于活脑灵治疗前后分别观察其神经功能缺损程度、评分改变情况。结果：活脑灵治疗１５ｄ后，少数病例有所改善，但神经功能缺损程度总评分变化不显著（Ｐ＞０．０５），而治疗３０ｄ后，神经功能缺损程度总评分显著减少（Ｐ＜０．０５）。结论：脑血管疾病后遗症可选用活脑灵治疗。

OBJECTIVE:To evaluate the efficacy and safety of buflomedil in treatment of sequel in cerebrovascular disease.METHODS:To observe the changes in total score of neurological functional damage in 31 patients before and after treated with buflomedil.RESULTS:Changes in total score of neurological functional damage were insignificant after 15 d treatment but it decreased significantly after 30 days treatment with buflomedil.CONCLUSION:The results of this trial suggested that buflomedil maybe a useful agent for treatment of sequel in cerebrovascular disease but the treatment should exceeded 30 days.