临沂市自然人群乙肝病毒感染状况调查

SURVEY AND ANALYSIS ON HBV INFECTION STATE OF NATURAL POPULATION IN LINYI CITY

了解临沂市自然人群HBV感染状况。方法整群、分层抽样确定调查对象，抽血检测HBsAg、抗-HBs、抗-HBc、HBeAg。结果自然人群乙肝患病率为48．06／10万，HBSAg、抗-HBS、抗-HBC阳性率及HBV感染率分别为7．11％、23．64％、27．72％和46．59％。年龄上有0～10岁和20～40岁两个感染高峰，40岁后随年龄增高而降低。HBSAg阳性具有明显的家庭聚集性，阳性父母的子女感染HBV的相对危险性成倍递增。阳性者随其滴度增高HBeAg检出率也增高，二者是正相关。抗-HBc、HBV感染率三项指标分布情况与HBSAg的分布相似。结论临沂市属于乙肝中等感染地区，有53．41％的人是易感者，应加强卫生防护。

Objective To find out HBV infection state of natural population in LinyiCity. Methods Survey objects were determined by chester and stratified samplings,andthe HBsAg, anti -- HBs, anti -- HBc and HBeAg were tested by hemospaisia. Results Themorbidity rate of HB in natural population was 418. 06/105,and the positive rate of HBsAg,anti -- HBs, and anti -- HBc were 7. 11 %, 23. 64 %and 27. 27% respectively. The infection rate of HBV was 46. 59%. There was two high infection climaxes between theage of 0-- 10 and 20-- 24 years old and after 40 years old,the positive rate was decreasingwith the age growing. The positve rate of HBsAg was characterized by its obvious familyclustering, the relative risk of infecting HBV in children with HBsAg positive parentswas redoubled and the detectable rate of HBeAg was also increased with the increase ofthe titre of the positive HBsAg. There was positive correlation between HBsAg andHBeAg. The distribution of anti -- HBs, anti -- HBc and the infection rate of HBV wassimilar to HBsAg. Conclusion Linyi City beglongs to moderate infective area of HB with53. 41% of the population being the susceptible and so sanitary protection should beaugmented to prevent infection of HB.