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调节性B细胞与炎症性肠病

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摘要 B细胞能够针对自身抗原产生相应的抗体,在自身免疫性疾病的发生和发展中发挥重要的作用。近年来的研究发现部分B细胞具有调节功能,这部分B细胞被命名为调节性B细胞,调节性B细胞可以分泌白细胞介素-10、转移生长因子-β1等细胞因子,中和病理性T细胞,或是直接与其它免疫细胞结合,抑制免疫应答。此综述初步探讨调节性B细胞在炎症性肠病中的作用及其可能机制。
作者 叶欣 赵洪川
出处 《国际消化病杂志》 CAS 2009年第6期415-417,共3页 International Journal of Digestive Diseases
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