海因类化合物的研究(Ⅰ)

STUDIES ON HYDANTOIN DERIVATIVES (Ⅰ)

本文合成了1，3－双（β－环氧丙基）－5，5－二甲基海因化合物。讨论了原料的配比、反应温度、溶剂等因素对海因化合物的影响，并用红外、核磁和端基分析、元素分析等手段对产物进行了分析。当环氧氯丙烷／海因摩尔比为2：1异丙醇作溶剂，反应温度低于100℃并在氮气保护下，可以获得目标产物。

1, 3-Di (β-epoxypropyl 1-5, 5-dimethyl hydantoin was formed of 5, 5-dimethyl hydantoin and epichlorohydrin. The effect of hydantoin/epichlorohydrin mol/ratio, solveut and reaction temperature on properties of product was studied in this paper. Its structure was studied by IR, NMR and ele-mentary analysis etc. The preferred reaction conditions were as follows hy-dantoin/epichlorohydrin mol ratio was 2: 1, isopropanol was used as solvent, the reaction temperature was below 100℃ under the protaction of nitrogen gas.